What is bioinformatics?

In biology, bioinformatics is defined as, “the use of a computer to store, retrieve, analyze or predict the composition or structure of bio-molecules”. Bioinformatics is the application of computational techniques and information technology to the organization and management of biological data. Classical bioinformatics deals primarily with sequence analysis.

Aims of bioinformatics

• Development of a database containing all biological information.

• Development of better tools for data designing, annotation, and mining.

• Design and development of drugs by using simulation software.

• Design and development of software tools for protein structure prediction function, annotation, and docking analysis.

• Creation and development of software to improve tools for analyzing sequences for their function and similarity with other sequences

Biological databases

Biological data are complex, exception-ridden, vast, and incomplete. Therefore several databases have been created and interpreted to ensure unambiguous results. A collection of biological data arranged in a computer-readable form that enhances the speed of search and retrieval and is convenient to use is called a biological database. A good database must have updated information.

Importance of biological database

A range of information like biological sequences, structures, binding sites, metabolic interactions, molecular action, functional relationships, protein families, motifs, and homologous can be retrieved by using biological databases. The main purpose of a biological database is to store and manage biological data and information in computer-readable forms.

In this course, we learned about the different biological databases that are being used in bioinformatics and get to know a little bit about their details. Mainly these databases are divided into four categories and we learned about base by base. And explained the difference between the primary and secondary databases and explained their utilization in bioinformatics.

This course will be extremely helpful to students of data analysts and bioinformaticians because they use the databases a lot in their work.

If you guys have any questions or suggestions please let me know in the instructor's inbox I’ll try to answer all of your questions within 12 hours.

Genome Browser

This course is mainly about the primary database browser called UCSC. The University of California Santa Cruz (UCSC) Genome Browser is a popular Web-based tool for quickly displaying a requested portion of a genome at any scale, accompanied by a series of aligned annotation “tracks.” The annotations generated by the UCSC Genome Bioinformatics Group and external collaborators include genes.

It is an interactive website offering access to genome sequence data from a variety of vertebrate and invertebrate species and major model organisms, integrated with a large collection of aligned annotations. The Browser is a graphical viewer optimized to support fast interactive performance and is an open-source, web-based tool suite built on top of a MySQL database for rapid visualization, examination, and querying of the data at many levels. The Genome Browser Database, browsing tools, downloadable data files, and documentation can all be found on the UCSC Genome Bioinformatics website.

In this course, we will be mainly covering the utilization of the UCSC Genome Browser and performing the whole scenario on SARS-COV-2(a strain of coronavirus).

And mainly learning about the Table Browser. Table Browser is also used to calculate intersections between tracks, and to retrieve DNA sequences covered by a track.

All these videos will be divided into three parts containing the Introduction, Explanation, and Summary so All of you can easily understand the Course.